Lipase
Slices fats into fatty acids.

Workbench
- Works on
- Fats (triglycerides)
- Leaves
- Fatty acids and monoglycerides
- Made by
- Mostly your pancreas.
- Works in
- Small intestine (from the pancreas), after bile breaks the fat into droplets.
- Sound
- SLICE!

On the bench
Lipase (Pizza cutter)
A triglyceride: one glycerol backbone, three fatty-acid tails
Pick a link and cut it with the pizza cutter.
How it works
Most of the fat in food is triglyceride: three fatty-acid tails hooked onto a small backbone called glycerol. Fat doesn’t mix with water, so lipase can only get at the outside of a blob.
That’s why bile goes first and breaks blobs into tiny droplets. Then lipase from the pancreas slices off the two outer tails and leaves the middle one attached: two fatty acids and a monoglyceride, ready to absorb.
AnnouncerThe pizza cutter is a metaphor. Please do not put butter on a pizza cutter.
Lipase works at the surface of fat. Bile’s whole job is to make more surface.
Butter
Egg yolk
The rest of the kit
Some food has no tool at all. That’s the buffet.
Coming up next on Channel GG
Lactase
Opens up milk sugar (lactose).









Amylase
Alpha-galactosidase
Bromelain
Papain